Review for the management of vitamin B12 deficiency in diabetic patients on metformin

Authors

  • Saad Thamer Sedeeq Qatar University Health Center, Primary Health Care Corporation, Doha, Qatar
  • Zohor Ahmed Kamaleldin Mohamed Qatar University Health Center, Primary Health Care Corporation, Doha, Qatar
  • Al Anoud Saleh Al Fehaidi Qatar University Health Center, Primary Health Care Corporation, Doha, Qatar
  • Mohammad Jamil Mohammad Al Tamimi Qatar University Health Center, Primary Health Care Corporation, Doha, Qatar
  • Mohamed Abd Elhamid Qatar University Health Center, Primary Health Care Corporation, Doha, Qatar
  • Amina Ali Mohamed Muktar Qatar University Health Center, Primary Health Care Corporation, Doha, Qatar
  • Ehab Hamed Qatar University Health Center, Primary Health Care Corporation, Doha, Qatar

DOI:

https://doi.org/10.18203/2320-6012.ijrms20203091

Keywords:

Diabetes mellitus, Diabetic neuropathies, Metformin, Prevalence, Vitamin B12 deficiency

Abstract

Long-term usage of Metformin is associated with lower serum vitamin B12 levels. The lower than normal levels could worsen neurological complications of diabetes, including diabetic neuropathy and poor cognition. Guidelines advise periodic monitoring of vitamin B12 but do not specify frequency, treatment targets or treatment modality. This commentary aims to review the prevalence and the severity of the presentation and to provide evidence-based answers to those clinical questions not answered by current guidelines.

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Published

2020-07-24

How to Cite

Sedeeq, S. T., Mohamed, Z. A. K., Al Fehaidi, A. A. S., Al Tamimi, M. J. M., Elhamid, M. A., Muktar, A. A. M., & Hamed, E. (2020). Review for the management of vitamin B12 deficiency in diabetic patients on metformin. International Journal of Research in Medical Sciences, 8(8), 3141–3146. https://doi.org/10.18203/2320-6012.ijrms20203091

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Section

Review Articles