Alveolar soft part sarcoma of extremity

Authors

  • Shilpa Kaushal Department of Radiotherapy and Oncology, Dr. RPGMC, Kangra at Tanda, Himachal Pradesh, India
  • Muninder K. Negi Department of Radiotherapy and Oncology, Dr. RPGMC, Kangra at Tanda, Himachal Pradesh, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20204263

Keywords:

Alveolar soft-part sarcoma, Pathology, Surgery, Radiotherapy

Abstract

Alveolar soft-part sarcoma (ASPS) is an extremely rare connective tissue tumor, predominantly seen in adolescents and young adults, with a female preponderance. Alveolar soft-part sarcoma (ASPS) is a slow growing tumor, but with high likelihood of metastasis, leading to high mortality. A classical histopathological feature of an alveolar pattern from the biopsy of the lesion favors the diagnosis. We report a case of 14 years old male patient who presented with a history of single painless swelling over thigh for which surgical excision was done. Histopathology was suggestive of Alveolar soft-part sarcoma (ASPS). There was no evidence of distant metastases. He was treated with external beam radiotherapy in view of vascular invasion.

References

Board A. Adult Soft Tissue Sarcoma Treatment (PDQ®): Patient Version. PDQ Cancer Information Summaries [Internet]. 2002.

Fletcher M, Bridge A, Hogendoorn W, Mertens F, eds. Pathology and Genetics of Tumours of Soft Tissue and Bone. Vol 5. Lyon, France: IARC Press; 2013:218.

Kayton ML, Meyers P, Wexler H, Gerald L, LaQuaglia P. Clinical presentation, treatment, and outcome of alveolar soft part sarcoma in children, adolescents, and young adults. J Pediatr Surg 2006;41:187-93.

Lieberman H, Brennan F, Kimmel M, Erlandson A, Garin-Chesa P, Flehinger Y. Alveolar soft-part sarcoma. A clinico-pathologic study of half a century. Canc. 1989;63:1-13.

Portera A, Ho V, Patel R, Hunt K, Feig W, Respondek M, et al. Alveolar soft part sarcoma: clinical course and patterns of metastasis in 70 patients treated at a single institution. Canc. 2001;91:585-91.

Suh S, Cho J, Lee H, Shin H, Yang I, Lee H, et al. Alveolar soft part sarcoma: MR and angiographic findings. Skeletal Radiol. 2000;29(12):680-89.

Evans L. Alveolar soft-part sarcoma. A study of 13 typical examples and one with a histologically atypical component. Canc. 1985;55:912-17.

Ogose A, Yazawa Y, Ueda T, Hotta T, Kawashima H, Hatano H, et al. Japenese Musculoskeletal Oncology Group. Alveolar soft part sarcoma in Japan: multi-institutional study of 57 patients from the Japanese Musculoskeletal Oncology Group. Oncol. 2003;65(1):7-13.

Pennacchioli E, Fiore M, Collini P, Radaelli S, Dileo P, Stacchiotti S, et al. Alveolar soft part sarcoma: Clinical presentation, treatment, and outcome in a series of 33 patients at a single institution. Ann Surg Oncol. 2010;17(12):3229-33.

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Published

2020-09-24

How to Cite

Kaushal, S., & Negi, M. K. (2020). Alveolar soft part sarcoma of extremity. International Journal of Research in Medical Sciences, 8(10), 3735–3737. https://doi.org/10.18203/2320-6012.ijrms20204263

Issue

Section

Case Reports