Study on correlation between six minute walk test and BODE index in chronic obstructive pulmonary disease patients


  • Babulal Bansiwal Department of Respiratory Medicine, GMC, Kota, Rajasthan, India
  • Anees K. V. Department of Pulmonary medicine, FHC Pulingome, Kannur, Kerala, India
  • Maneesha Jelia Department of Anatomy, GMC, Kota, Rajasthan, India
  • Satyam Agarwal Department of Respiratory Medicine, GMC, Kota, Rajasthan, India



Chronic obstructive pulmonary disease, Indian council of medical research, BODE, 6 MWT


Background: Chronic obstructive pulmonary disease is preventable and treatable disease with progressive persistent airflow limitation and enhanced chronic inflammatory response in the airways. Indian council of medical research conducted a study and found that total burden of COPD in India has more than doubled to about 14.84 million in 2011 from about 6.45 million in 1971

Methods: It was an open label cross sectional study. It was conducted on patients attending the outpatient department of respiratory medicine, new medical college and hospital, Kota, over a period of one year. 100 COPD patients attending the respiratory outpatient department of GMC, Kota and fulfilling the inclusion criteria’s were included in the study. A diagnosis and severity of COPD was established by clinical symptoms and spirometric data as per GOLD guideline (ratio of FEV1 and forced vital capacity <0.7).

Results: We found a significant negative correlation (Pearson correlation coefficient r = -0.664, p< 0.001) between 6 MWD and BODE index in study population.

Conclusions: Thus, we concluded that the functional exercise capacity of COPD patients measured by 6MWT deteriorates linearly with severity of the disease assessed by the GOLD staging criteria. Hence we can use 6 MWT for assessing the severity of COPD in place of spirometry where the facility of spirometry is not feasible.

Author Biography

Babulal Bansiwal, Department of Respiratory Medicine, GMC, Kota, Rajasthan, India

department of Respiratory medicine,GMC,KOTA



Global strategy for diagnosis, management, and prevention of COPD. Available at: http://goldcopd. org/global-strategy-diagnosis-management-prevention-copd-2016/. Accessed on 10 June 2020.

Murray CJ, Lopez AD. Evidence based health policy lessons from the global burden of disease study. Science. 1996;274:7403.

Casanova C, Cote CG, Marin JM, Torres JP, Aguirre-Jaime A, Mendez R, et al. The 6-min walking distance: Long-term follow up in patients with COPD. Eur Respir J. 2007;29:535-40.

Borg GAV. Psycho-physical bases of perceived exertion. Med Sci Sports Exerc. 1982;14:377-81.

Enright PL, Sherrill DL. Reference equations for the six-minute walk in healthy 16] adults. Am J RespirCrit Care Med. 1998;158:1384-87.

Chuang ML, Lin IF, Wasserman K. The body weight-walking distance product as related to lung function, anaerobic threshold and peak VO2 in COPD patients. Respir Med. 2001;95:618-26.

Shapiro SD, Ingenito EP. The pathogenesis of chronic obstructive pulmonary disease: advances in the past 100 years. Am J Respir Cell Mol Biol. 2005;32:367-72.

Wasserman K, Hansen JE, Sue DY, Casaburi R, Whipp BJ. Principles of exercise testing and interpretation, 3rd ed. Philadelphia: Lippincott; 1999:116.

Weisman IM, Zeballos RJ. An integrated approach to the interpretation of cardiopulmonary exercise testing. Clin Chest Med. 1994;15:421-45.

Celli BR, Cote CG, Marin JM, et al: The Body mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N Engl J Med. 2004;350:1005-012.

Santana P, Cintra RM, Rodrigues F, Casanova C, Oca MM, Mendez RA, et al. Correlation study on the result from measures of function and functionality test of COPD patients. Available at: Accessed on 10 June 2020.

Landbo C, Prescott E, Lange P, Vestbo J, Almdal TP. Prognostic value of nutritional status in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1999;160:1856-61.




How to Cite

Bansiwal, B., V., A. K., Jelia, M., & Agarwal, S. (2020). Study on correlation between six minute walk test and BODE index in chronic obstructive pulmonary disease patients. International Journal of Research in Medical Sciences, 8(11), 3911–3915.



Original Research Articles