Prevalence and risk factors associated with depressive symptoms among end-stage renal disease patients undergoing hemodialysis in Indian setting

Rajeev Kumar Bhatia; Ajay Marwaha

doi:10.18203/2320-6012.ijrms20205830

Authors

Rajeev Kumar Bhatia Department of Nephrology, Shrimann Superspeciality Hospital, Pathankot Road, Jalandhar, Punjab, India
Ajay Marwaha Department of Nephrology, Shrimann Superspeciality Hospital, Pathankot Road, Jalandhar, Punjab, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20205830

Keywords:

Anxiety, Anxiety and stress scale-21, Depression, Quality of life.

Abstract

Background: This study aimed to evaluate the prevalence of depressive symptoms among the patients with end-stage renal disease (ESRD) on hemodialysis and to explore associated risk factors.

Methods: A prospective observational study of patients with ESRD undergoing hemodialysis were included in the study. Data was collected based on questionnaire created by the study team, and by verbal interviews with patients. The questionnaire consisted of two parts, which included demographic data (gender, age, sleep quality, duration of sleep, appetite pattern, and duration of dialysis) and evaluation of the severity of depressive symptoms by using the depression, anxiety and stress scale-21.

Results: Out of total 93 patients with ESRD on hemodialysis majority of patients belonged to the age group of >60 to ≤80 years (47.8%) and age group >40 to ≤60 years (40.0%). Patients had a higher incidence of severe anxiety (38.7%) than depression (34.4%), and stress (22.6%). The proportion of patients diagnosed with depression (50.0%) and stress (57.1%) was higher in the older age group (>60 to ≤80 years); while the proportion of patients having severe anxiety was similar in both adult (>40 to ≤60 years) and older (>60 to ≤80 years) age group (38.9%). More than 50% of patients with depressive, anxiety, and stress symptoms had insufficient sleep (≤1 to ≤4 h). The present study could not predict the risk factors of depressive symptoms in patients with ESRD on hemodialysis.

Conclusions: Depression and anxiety symptoms were more frequent among patients with ESRD undergoing hemodialysis in Indian settings.

Metrics

Metrics Loading ...

References

Vaidya SR, Aeddula NR. Chronic Renal Failure. In: StatPearls. Treasure Island (FL): Stat Pearls. Available at: https://www.ncbi.nlm.nih.gov/books/ NBK535404/. Accessed on 26 June 2020.

Al Dukhayel A. Prevalence of Depressive Symptoms among Hemodialysis and Peritoneal Dialysis Patients. Int J Health Sci (Qassim). 2015;9:9-16.

Boris B. Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2020;395:709-33.

Carney EF. The impact of chronic kidney disease on global health. Nat Rev Nephrol. 2020;16:251.

Rahimi F, Rejeh N, Bahrami T, Heravi-Karimooi M, Tadrisi SD, Griffiths P, et al. The effect of the eye movement desensitization and reprocessing intervention on anxiety and depression among patients undergoing hemodialysis: A randomized controlled trial. Perspect Psychiatr Care. 2019;55:652-60.

Jankowska-Polanska B, Uchmanowicz I, Wysocka A, Uchmanowicz B, Lomper K, Fal AM. Factors affecting the quality of life of chronic dialysis patients. Eur J Public Health. 2017;27:262-7.

Mehrabi Y, Ghazavi Z, Shahgholian N. Effect of Fordyce's Happiness Program on Stress, Anxiety, and Depression among the Patients Undergoing Hemodialysis. Iran J Nurs Midwifery Res. 2017;22:190-94.

Dąbrowska-Bender M, Dykowska G, Żuk W, Milewska M, Staniszewska A. The impact on quality of life of dialysis patients with renal insufficiency. Patient Prefer Adherence. 2018;12:577-83.

Kimmel PL, Peterson RA. Depression in patients with end-stage renal disease treated with dialysis: has the time to treat arrived?. Clin J Am Soc Nephrol. 2006;1:349-52.

Nagasawa H, Sugita I, Tachi T, Esaki H, Yoshida A, Kanematsu Y, et al. The Relationship Between Dialysis Patients' Quality of Life and Caregivers' Quality of Life. Front Pharmacol. 2018;9:770.

Chiang HH, Livneh H, Yen ML, Li TC, Tsai TY. Prevalence and correlates of depression among chronic kidney disease patients in Taiwan. Bio Med Centr Nephrol. 2013;14:78.

Goh ZS, Griva K. Anxiety and depression in patients with end-stage renal disease: impact and management challenges- a narrative review. Int J Nephrol Renovasc Dis. 2018;11:93-102.

Teles F, Azevedo VF, Miranda CT, Miranda MP, Teixeira Mdo C, Elias RM. Depression in hemodialysis patients: the role of dialysis shift. Clinics (Sao Paulo). 2014;69:198-202.

Bachmann S. Epidemiology of Suicide and the Psychiatric Perspective. Int J Environ Res Pub Heal. 2018;15:1425.

Khan A, Khan AH, Adnan AS, Sulaiman SAS, Mushtaq S. Prevalence and predictors of depression among hemodialysis patients: a prospective follow-up study. Bio Med Cent Pub Heal. 2019;19:531.

Jiang LC, Yan YJ, Jin ZS, Hu ML, Wang L, Song Y, et al. The Depression Anxiety Stress Scale-21 in Chinese Hospital Workers: Reliability, Latent Structure, and Measurement Invariance Across Genders. Front Psychol. 2020;11:247.

González-Rivera JA, Torres P, Pagán-Torres OM, Pérez-Torres EM. Depression, Anxiety and Stress Scales (DASS-21): Construct Validity Problem in Hispanics. Europ J Investigat Heal Psychol Educat. 2020;10:375-89.

Hawamdeh S, Almari AM, Almutairi AS, Dator WLT. Determinants and prevalence of depression in patients with chronic renal disease, and their caregivers. Int J Nephrol Renovasc Dis. 2017;10:183-9.

Antony M, Bieling PJ, Cox BJ, Enns MW, Swinson RP. Psychometric properties of the 42-item and 21-item versions of the Depression Anxiety Stress Scales in clinical groups and community a sample. Psychological Assessment. 1998;10:176-81.

Lovibond SH, Lovibond PF. Manual for the Depression Anxiety Stress Scales. 2nd ed. Sydney: Psychol Foundat. 1995;33:335-43.

Sharma K, Gupta A, Sharma RC, Mahajan N, Mahajan A, Sharma D. Prevalence and risk factors for depression in elderly North Indians. 2016;3:158-63.

Hedayati SS, Yalamanchili V, Finkelstein FO. A practical approach to the treatment of depression in patients with chronic kidney disease and end-stage renal disease. Kidney Int. 2012;81:247-55.

Banu Terzi B, Topbaş E, Ergül HC. Comparison of sleep quality and dialysis adequacy of patients undergoing hemodialysis. 2019;30:1342-50.

Goyal E, Chaudhury S, Saldanha D. Psychiatric comorbidity in patients undergoing hemodialysis. Ind Psychiatry J. 2018;27:206-12.

Mosleh H, Alenezi M, Al Johani S, Alsani A, Fairaq G, Bedaiwi R. Prevalence and Factors of Anxiety and Depression in Chronic Kidney Disease Patients Undergoing Hemodialysis: A Cross-sectional Single-Center Study in Saudi Arabia. Cureus. 2020;12:e6668.

Micol A, Moss-Morris R, Caskey F, Chilcot J. Fatigue in advanced kidney disease. Kidney Int. 2014;86:497-505.

Chan L, Tummalapalli SL, Ferrandino R, Poojary P, Saha A, Chauhan K, et al. The Effect of Depression in Chronic Hemodialysis Patients on Inpatient Hospitalization Outcomes. Blood Purif. 2017;43:226-34.

Kim JW, Moon SJ, Kim HJ, Lee DG. Relationship between chronic kidney disease and depression in elderly Koreans using the 2013 Korea National Health and Nutrition Examination Survey Data. Korean J Fam Med. 2017;38:156-62.

Shirazian S, Grant CD, Aina O, Mattana J, Khorassani F, Ricardo AC. Depression in Chronic Kidney Disease and End-Stage Renal Disease: Similarities and Differences in Diagnosis, Epidemiology, and Management. Kidney Int Rep. 2016;20:94-107.

Maung SC, El Sara A, Chapman C, Cohen D, Cukor D. Sleep disorders and chronic kidney disease. World J Nephrol. 2016;5:224-32.

Cukor D, Coplan J, Brown C, Peterson RA, Kimmel PL. Course of depression and anxiety diagnosis in patients treated with hemodialysis: a 16-month follow-up. Clin J Am Soc Nephrol. 2008;3:1752-8.

Griva K, Kang AW, Yu ZL, Mooppil NK, Foo M, Chan CM, et al. Quality of life and emotional distress between patients on peritoneal dialysis versus community-based hemodialysis. Qual Life Res. 2014;23:57-66.

Bujang MA, Musa R, Liu WJ, Chew TF, Lim CT, Morad Z. Depression, anxiety and stress among patients with dialysis and the association with quality of life. As J Psychiatr. 2015;18:49-52.

Huang CW, Wee PH, Low LL, Koong YLA, Htay H, Fan Q, et al. Prevalence and risk factors associated with Anxiety Symptoms and Disorders Among Chronic Kidney Disease patients- A Systematic Review and Meta-analysis of studies. 2020.

Hamzi MA, Hassani K, Asseraji M, El Kabbaj D. Insomnia in hemodialysis patients: A multicenter study from morocco. Saudi J Kidney Dis Transpl. 2017;28:1112-8.

Keskin G, Babacan Gümüş A, Taşdemir Yiğitoğlu G. Sexual dysfunctions and related variables with sexual function in patients who undergo dialysis for chronic renal failure. J Clinic Nurs. 2019;28(1-2):257-69.

Einollahi B, Motalebi M, Rostami Z, Nemati E, Salesi M. Sleep quality among Iranian hemodialysis patients: a multicenter study. Nephrourol Mon. 2014;7:e23849.