Published: 2020-09-24

Rhabdomyolysis with acute kidney injury after single episode of generalized seizure in a known case of epilepsy: a case report

Sudhakar Pandey, Nomal C. Borah, Manjari Dwivedi, Rup J. Das


Rhabdomyolysis is defined as breakdown of skeletal muscle fibers with subsequent release of its cellular components into the circulation. It is associated with variety of causes and status epilepticus is one of it. The excessive muscular activity associated with seizure is possible explanation for it. It is clinically evident by the new onset severe generalized bodyache, weakness and myalgia associated with dark coloured urine. Acute kidney injury is one of the most serious complications associted with rhabdomyolysis. Single episode of generalized seizure is not a frequent cause for rhabdomyolysis. Acute kidney injury due to rhabdomyolysis, following a single episode of seizure is a rare entity. Here we report a case of rhabdomyolysis with acute kidney injury following a single episode of generalized seizure. High index of suspicion is required to timely diagnose and treat such patients. Timely intervention with hemodialysis along with other supportive care can completely revert this potentially serious complication to normal.


Rhabdomyolysis, Acute kidney injury, Seizure, Myoglobinuria, Creatine phosphokinase

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