Metabolic syndrome in south Indian population with skin tags: a hospital-based case control study

Bobbili Tarun Kesava Naidu; Kavya Baddireddy

doi:10.18203/2320-6012.ijrms20204251

Authors

Bobbili Tarun Kesava Naidu Department of General Medicine, GVP Institute of Health Care and Medical Technology, Visakhapatnam, Andhra Pradesh, India
Kavya Baddireddy Department of Dermatology, Venereology and Leprology, GVP Institute of Health Care and Medical Technology, Visakhapatnam, Andhra Pradesh, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20204251

Keywords:

Metabolic syndrome, Skin tags, Dyslipidaemia, Diabetes, Hypertension

Abstract

Background: Metabolic syndrome is a constellation of several clinical and laboratory cardiovascular risk factors that have been linked with numerous medical and dermatologic conditions. Recent evidence suggests a strong association between skin tags and insulin resistance and obesity, yet there is a paucity of data on relation of skin tags with metabolic syndrome as a whole. Aim of the study was to evaluate the strength of association between skin tags and metabolic syndrome.

Methods: 70 patients with skin tags and an equal number of age and gender matched controls were enrolled in a hospital-based case control study. Anthropometric measures, blood pressure, fasting glucose, high density lipoprotein cholesterol and triglycerides were measured. Metabolic syndrome was diagnosed by the presence of 3 or more of the south Asian modified national cholesterol education program’s adult panel III criteria. Statistical analysis was performed using chi square test, and odds ratio was calculated. P≤0.05 were considered significant.

Results: Metabolic syndrome was significantly more common in patients with skin tags than in controls (70% vs. 26%, p<0.001). Triglycerides and waist circumference values were significantly increased in cases as compared to controls (p<0.05). There was no statistically significant difference in the high-density lipoprotein levels, fasting blood glucose levels and presence of hypertension among cases and controls.

Conclusion: Skin tags when present in multiple could be an early warning sign for Metabolic syndrome. They serve a cutaneous marker to initiate early detection and intervention of at-risk patients for cardiovascular disorders.

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Author Biographies

Bobbili Tarun Kesava Naidu, Department of General Medicine, GVP Institute of Health Care and Medical Technology, Visakhapatnam, Andhra Pradesh, India

Assistant Professor

Department of General Medicine

Kavya Baddireddy, Department of Dermatology, Venereology and Leprology, GVP Institute of Health Care and Medical Technology, Visakhapatnam, Andhra Pradesh, India

Department of Dermatology, Venereology & Leprology

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