Comparison between isobaric levobupivacaine 0.5% and hyperbaric bupivacaine 0.5% in spinal anesthesia in lower limb surgeries and lower abdominal surgeries in adult patients

Authors

  • Preeti Parashar Department of Department of Anesthesia and Critical Care, M. P. Shah Medical College, Jamnagar, Gujarat, India
  • Anisha Singh Department of Anesthesia and Critical Care Maulana Azad Medical College, New Delhi, India
  • Manoj Kumar Sharma Department of Cardiology, Batra Hospital and Medical Research Centre, New Delhi, India
  • Dipak L. Raval Department of Department of Anesthesia and Critical Care, M. P. Shah Medical College, Jamnagar, Gujarat, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20210417

Keywords:

Key words, spinal, anesthesia, levobupivicaine, bupivacaine

Abstract

 

Background: The aim of our study was to compare sensory and motor block characteristics and hemodynamic changes following intrathecal hyperbaric bupivacaine (0.5%) and isobaric levobupivacaine (0.5%) in elective lower limb and lower abdominal surgeries.

Methods: 60 patients of either sex, aged 18-60 years, ASA grade I or II scheduled for elective lower abdominal and lower limb surgeries were randomized into two groups, group B (n=30) and group L (n=30) and received either 3 ml of intrathecal hyperbaric bupivacaine or isobaric levobupivacaine intrathecally.

Results: The mean time of onset of sensory block at shin of tibia in both the groups was comparable i.e. levobupivacaine (1.19±0.2 minutes) and bupivacaine (1.1+0.2 minutes). The mean time for total duration of sensory block was 211.1±8.2 minutes in group L, while 193.13±13.7 minutes in group B. Time for total duration of motor block in group L was 198.76±8.428 minutes and in group B was 182.6±13.989 minutes. Statistically significant difference was observed in total duration of sensory and motor block in both levobupivaciane and bupivacaine group (p<0.0001). Patients in group L were hemodynamically more stable with significantly less decrease in pulse rate, systolic blood pressure and diastolic blood pressure as compared to group B.

Conclusions: We observed that 0.5% isobaric levobupivacaine provided better hemodynamic stability, longer duration of sensory and motor block as compared to bupivacaine.

 

Author Biographies

Preeti Parashar, Department of Department of Anesthesia and Critical Care, M. P. Shah Medical College, Jamnagar, Gujarat, India

SENIOR RESIDENT,DEPARTMENT OF ANAESTHESIOLOGY AND CRITICAL CARE

Anisha Singh, Department of Anesthesia and Critical Care Maulana Azad Medical College, New Delhi, India

SENIOR RESIDENT,DEPARTMENT OF ANAESTHESIOLOGY AND CRITICAL CARE

Manoj Kumar Sharma, Department of Cardiology, Batra Hospital and Medical Research Centre, New Delhi, India

DNB Senior resident,Department of Cardiology,

Dipak L. Raval, Department of Department of Anesthesia and Critical Care, M. P. Shah Medical College, Jamnagar, Gujarat, India

Additonal Professor, Department of  Anaesthesiology & Critical Care,

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Published

2021-01-29

How to Cite

Parashar, P., Singh, A., Sharma, M. K., & Raval, D. L. (2021). Comparison between isobaric levobupivacaine 0.5% and hyperbaric bupivacaine 0.5% in spinal anesthesia in lower limb surgeries and lower abdominal surgeries in adult patients. International Journal of Research in Medical Sciences, 9(2), 418–422. https://doi.org/10.18203/2320-6012.ijrms20210417

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Original Research Articles