Mucosa-associated lymphoid tissue lymphoma of the appendix stump: a case report

Uraik F. Hernandez.Bustos, Jonathan Salgado-Vives, Enrique Chavez-Serna, Dante A. Saldivar-Vera, Elí D. Hernández-Gómez, Pedro A. Alvarado-Bahena, Pedro A. Espinosa de los Monteros-Moranchel


Primary lymphomas of the appendix occur in 0.015% of all gastrointestinal lymphomas. The most common manifestation is acute appendicitis secondary to luminal obstruction. The most common is immunophenotype B low-grade non-Hodgkin lymphoma. A 53-year-old male, with a previous three-week surgical history due to acute appendicitis, histopathological report of acute appendicitis and lymphoid hyperplasia. Later, he was admitted, with abdominal pain in the right iliac fossa, an abdominal ultrasound and simple abdominal tomography were performed, with suspicion of residual abscess. Surgical intervention is decided, observing paracecal tumor in the emergency site of the appendix, the tumor is removed. Pathological study that reports an appendicular base infiltrated by mucosa-associated lymphoma. The diagnosis of appendicular tumors is mostly, intraoperatively incidental. It is necessary to have the diagnostic possibility when performing an appendectomy, since it changes the prognosis and treatment of the patient.


Appendicitis surgery, Stump appendicitis, Mucosal associated lymphoma, Appendicitis

Full Text:



Murguía-Perez M. Serrano-Rufino M. Bolaños-Aguilar M. Mendoza-Ramirez S. Linfoma primary appendix cecal with clinical presentation of acute appendicitis. Rev Esp Patol. 2013;46:101-5.

Villegas-Tovar E, González-Chávez MA, Lemus-Ramírez RI, López-Ramírez AY, Faes-Petersen R, Gidi AD, et al. Appendicular tumors as a cause of appendicitis. 10 years’ experience in a private hospital. Medica Sur. 2016;22(2):76-81.

Villegas-Tovar E, González-Chávez MA, Lemus-Ramírez RI, López-Ramírez AY, Faes-Petersen R, Gidi AD, et al. Tumores apendiculares como causa de apendicitis aguda. Experiencia de 10 años en un hospital privado. Medica Sur. 2016;22(2):76-81.

Beltrán S, Marcelo A, Tapia L, Rodrigo, Madariaga G, Juan, et al. Malignant tumors of the appendix in patients undergoing appendicitis in the IV Region of Chile. Chilea Magaz Surg. 2013;65(6):509-14.

García-Norzagaray JC, Villalobos-López JA, Flores-Nájera H, Valle JL, García CT. Primary lymphoma of the appendix: A case report and review of the literature. J Gastroenterol Mex. 2018

Chae M, Kumar S, Cheema M. Mantle cell lymphoma presenting as acute appendicitis. Int J Surg Case Rep. 2015;6C:33-5.

Gómez J., Membreño L. Valle R. Valladare J. Linfoma of the appendix cecal with clinical presentation of appendicitis aguda proposed a case. Rev Md Hondur. 2016;84(1-2):52-4.

Misdraji, J. Mucinous epithelial neoplasms of the appendix and pseudomyxoma peritonei. Mod Pathol. 2015;28:S67-9.

Zamorano M, Quiroz M, Drolett SFN, Carrasco C. Neoplasias malignas primarias del apéndice cecal: estudio comparativo entre 2 hospitales regionales. Chilea Magaz Surg. 2014;66(6):543-8.

Martínez LE, Valanci Aroesty S, Belmonte Montes C. Incidence of tumors in the appendix at the ABC Medical Center. Medic Analys Medic Assoc ABC Medic Cent. 2009;54(4):201-5.