Histopathological spectrum of salivary gland lesions - in a tertiary care centre

Authors

  • Gomathi Srinivasan Department of Pathology, Stanley Medical College, Chennai, Tamil Nadu, India
  • Francis Asir Joseph J. Department of Pathology, Stanley Medical College, Chennai, Tamil Nadu, India
  • Shanmugam Kaliyaperumal Department of Pathology, Stanley Medical College, Chennai, Tamil Nadu, India
  • Arunalatha Ponnaiah Department of Pathology, Stanley Medical College, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20205658

Keywords:

Salivary gland, Benign tumors, Malignant tumors

Abstract

ABSTRACT

 

Background: Histopathology is the most important means in diagnosis of salivary gland lesions. The objective of this study is, to study occurrence of salivary lesions during a period of one year from January 2019 to December 2019, to study age, sex and site distribution of various salivary gland lesions, to study histo-morphological aspect of these lesions.

Methods: Surgically resected salivary gland specimens received at Department of Pathology, Government Stanley Medical College, Chennai were subjected to histopathological examination. Specimens were fixed in 10% neutral buffered formalin, processed, embedded, sections cut and stained with hematoxylin and eosin stain.

Results: There were a total of 30 salivary gland specimens. Out of thirty, 25 were neoplastic and 5 were non-neoplastic. Pleomorphic adenoma was the commonest of all benign tumors. Mucoepidermoid carcinoma was the most common malignant tumor. Among the 21 benign tumors, 16 cases of pleomorphic adenoma and a case each of myoepithelioma, benign metastasising pleomorphic adenoma, basal cell adenoma, warthins tumor and schwannoma were found. Among the 4 malignant tumors, 2 cases of mucoepidermoid carcinoma, a case of carcinoma ex pleomorphic adenoma and a case of myoepithelial carcinoma were found. Among the 5 non neoplastic lesions a case each of chronic sialadenitis, Sjogren’s syndrome, inflammatory myofibroblastioc tumor, parotid abscess and lymphoepithelial cyst were found.

Conclusions: The diagnosis of salivary gland lesions by histopathological examination is the most important method in diagnosis and differentiating benign and malignant lesions and to predict prognosis by typing, staging and grading of malignant neoplasms.

Author Biographies

Gomathi Srinivasan, Department of Pathology, Stanley Medical College, Chennai, Tamil Nadu, India

Associate Professor of Pathology

Francis Asir Joseph J., Department of Pathology, Stanley Medical College, Chennai, Tamil Nadu, India

Assistant Professor of Pathology

Shanmugam Kaliyaperumal, Department of Pathology, Stanley Medical College, Chennai, Tamil Nadu, India

Assistant Professor of Pathology

Arunalatha Ponnaiah, Department of Pathology, Stanley Medical College, Chennai, Tamil Nadu, India

Professor & HOD of Pathology

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Published

2020-12-28

How to Cite

Srinivasan, G., J., F. A. J., Kaliyaperumal, S., & Ponnaiah, A. (2020). Histopathological spectrum of salivary gland lesions - in a tertiary care centre. International Journal of Research in Medical Sciences, 9(1), 97–101. https://doi.org/10.18203/2320-6012.ijrms20205658

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Original Research Articles