Importance of magnetic resonance imaging brain in metronidazole-induced cerebellar ataxia- a case report
DOI:
https://doi.org/10.18203/2320-6012.ijrms20211382Keywords:
Metronidazole toxicity, Cerebellar ataxia, Liver abscessAbstract
Metronidazole is an antibiotic and an antiprotozoal drug, is cost effective treatment of choice in amoebic liver abscess. Cerebellar toxicity is quite rare and serious side effect of metronidazole, which is reversible. The importance of MRI brain in this condition is the typical finding of abnormal T2 as well as FLAIR hyperintensities in dentate nuclei and splenium of corpus callosum. We present a case of liver abscess on prolong metronidazole treatment presented with acute onset cerebellar ataxia.
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References
Neki NS, Joshi N, Rana D, Singh GD, Shergil, Singh G et al. Metronidazole toxicity presenting with cerebellar ataxia. Int J Curr Res Med Sci. 2017;3:10-3.
Patel K, Hopkins G. cerebellar ataxia following prolonged use of Metronidazole: case report and a literature review. Int J infectious dis. 2008;12:e111-4.
Woodruff BK, Wijdicks EF, Marshall WF. Reversible metronidazole-induced lesions of the cerebellar dentate nuclei. N Engl J Med. 2002;346:68-9.
Krige JEJ, Beckingham IJ. Liver abscesses and hydatid disease. BMJ. 2001;322(7285):537-40.
Ahmed A, Loes DJ, Bressler EL. Reversible magnetic resonance imaging findings in metronidazole-induced encephalopathy. Neurology. 1995;45:588-9.
Iqbal A, Tripathi K, Rai M, Dwivedi AN. Clinical and imaging perspective and unanswered questions in a case of metronidazole induced encephalopathy. Ann Indian Acad Neurol. 2013;16(4):569-71.
Ojha P, Chourasiya M, Shah H, Pandey V. Metronidazole induced Reversible Cerebellar Ataxia in a patient of multiple liver abscesses: a case report. Int J Biomed Adv Res. 2014;5:643-4.
Kalia V, Vibhuti, Saggar K. Case report: MRI of the brain in metronidazole toxicity. Indian J Radiol Imaging. 2010;20(3):195-7.