An observational study of clinical sequelae in COVID-19 at ESIC MCH Hyderabad
DOI:
https://doi.org/10.18203/2320-6012.ijrms20211877Keywords:
DVT, DM, Fibrosis, Fatigue, Kidney failure, MyalgiaAbstract
ABSTRACT
Background: covid 19 a deadly pandemic affecting people in 2020 not going to leave them without sequelae.This study is aimed at studying the sequelae in patients affected with covid 19.
Methods: This Prospective Observational study was done from July 2020 to October 2020 in ESIC MCH Hyderabad.The patients admitted with covid 19 symptoms were treated and discharged.The patients on their follow up in OPD were asked about the symptoms persisting.
Results: A total of 100 patients 60 males and 40 females presented during the study period.Most of the patients had fatigue 75[75%],myalgia 70[70%],dyspnea50[50%],throat pain 30[30%],edema 15[15%],dvt 10[10%],abdominal pain5[5%].Some of them developed DM due to use of steroids.
Conclusions: It was observed from the study that this deadly pandemic could have everlasting effect on the affected people.though people recovered from the illness patients had complaints of fatigue,myalgias,dyspnea etc.Patients having lung complications aggravated leading to fibrosis.it was observed that patients with covid infection had predilection for kidney failure,heart failure.
References
Huang C, Wang Y, Li X. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497-506.
Lu R, Zhao X, Li J. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020;395:565-74.
Zhu N, Zhang D, Wang W. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727-33.
World Health Organization. Coronavirus disease (COVID-19) outbreak March 25, 2021. Available at https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports. Accessed on 20 December 2020.
Chen N, Zhou M, Dong X. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020;395:507-13.
Wang D, Hu B, Hu C. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;323(11):1061-9.
Chen T, Wu D, Chen H. Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study. BMJ. 2020;368:1091.
Wu C, Chen X, Cai Y. Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China. JAMA Intern Med. 2020;180(7):934-43.
Richardson S, Hirsch JS, Narasimhan M. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City Area. JAMA. 2020;323(20):2052-9.
Verity R, Okell LC, Dorigatti I. Estimates of the severity of coronavirus disease 2019: a model-based analysis. Lancet Infect Dis. 2020;20(6):669-77.
Wang D, Hu B, Hu C. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;323(11):1061-9.
Livingston E, Bucher K. Coronavirus disease 2019 (COVID-19) in Italy. JAMA. 2020;323(14):1335.
Jordan RE, Adab P, Cheng KK. Covid-19: risk factors for severe disease and death. BMJ. 2020;368:1198.
Wambier CG, Goren A, Ossimetha A, Nau G, Qureshi AA. Theory androgen-driven COVID-19 pandemic theory. Early Hum dev. 2020;146:1050-74.
Estrogen C. Other sex hormones help men survive Covid-19? - The New York Times. Available at https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports. Accessed on 27 April 2020.
Stopsack KH, Mucci LA, Antonarakis ES, Nelson PS, Kantoff PW, Kettering S. TMPRSS2 and COVID 19 serendipity or opportunity for intervention? Cancer Discov. 2020;10(6):779-82.
Shastri A, Wheat J, Agrawal S. Delayed clearance of SARS-CoV2 in male compared to female patients: High ACE2 expression in testes suggests possible existence of gender-specific viral reservoirs. BMJ. 2020;368:606.
Huang I, Lim MA, Pranata R. Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia - a systematic review, meta-analysis, and meta-regression: diabetes and COVID-19. Diabetes Metab Syndr Clin. 2020;14(4):395-403.
Cariou B, Hadjadj S, Wargny M. Phenotypic characteristics and prognosis of inpatients with COVID-19 and diabetes: the CORONADO study. Diabetologia. 2020;63(8):1500-15.
Bornstein SR, Rubino F, Khunti K. Practical recommendations for the management of diabetes in patients with COVID-19. Lancet Diabetes Endocrinol. 2020;8:546-50.
Antoniou KM, Raghu G, Tzilas V, Bouros D. British thoracic society advice for managing interstitial lung disease patients during COVID-19 pandemic. Respiration. 2020;99:625-7.
Williamson E, Walker AJ, Bhaskaran KJ. Factors associated with COVID-19-related hospital death in the linked electronic health records of 17 million adult NHS patients. Nature. 2020;584:430-6.
Gianfrancesco M, Hyrich KL, Al-Adely S. Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 global rheumatology alliance physician-reported registry. Ann Rheum Dis. 2020;21:8713.
Dai M, Liu D, Liu M. Patients with cancer appear more vulnerable to SARS-COV-2: a multi-center study during the COVID-19 outbreak. Cancer Discov. 2020;20:422.
Cancer patients are nearly three times more likely to die of covid-19, study says - The Washington Post. Available at https://subscription.washingtonpost.com/e_di_ip_2yr59_dec20/?UTM_Promo=gse_di_ip_intl_in_2yr999_dec20&utm_source=google&utm_medium=acq-intl-in&utm_campaign=dr-search-evg&utm_content=intl_news_search_india&utm_keyword=the%20washington%20post&campaignid=11904740535&adgroupid=119225412647&gclid=CjwKCAjwjbCDBhAwEiwAiudBy42X7GLaDFcH1K6lH4wmTSr9j6igsNF0PYKVO2dBUlsmRxvpXBLEOxoC6zIQAvD_BwE. Accessed on 29 April 2020
