Aerobic bacterial pathogens in burn wound infections: experience in a teaching institution
Keywords:Burn wound infections, bacterial pathogens, Aerobic
Background: Infections are a serious cause of burn mortality and morbidity. Post initial resuscitation burn wound infections account for 75% of burn mortality. With rising number of multidrug resistant pathogens and changing microbiological colonizers of the burn wound, the insight provided by documenting the pathogens will help streamline the management. The aim of our study was to isolate, identify and study the profiles of aerobic bacteria in patients with burn wound infections.
Methods: This was a hospital based observational study carried out in the department of microbiology and department of burns and plastics, Safdarjung hospital after obtaining hospital ethical committee approval. Day 1, day 3, day 5 and day 10 swabs from burn sites were taken and processed after taking proper aseptic precautions from a total of 100 patients.
Results: Most of the aerobic isolates were gram negative in nature with K.pneumoniae (27.43%) being the most common followed by P. aeruginosa (22.12%), S. aureus (14.15%), P. mirabilis (10.61%), Acinetobacter spp (10.17%), CoNS (8.40%), E. coli (3.53%), P. stuartii (1.32%), Enterobacter spp (1.32%), K. oxytoca (0.44%) and C. koseri (0.44%).
Conclusions: We concluded the study recognizing K. pneumoniae as the most common isolate that cause burn wound infections. Further studies which include anaerobic isolates are required for identifying full range of organism profile of burn wound infections.
Burns. Available at: www.who.int/en/news-room/ fact-sheets/detail/burns. Accessed on 20 February 2021.
Gupta J, Makhija L, Bajaj S. National program for prevention of burn injuries. Indian J Plast Surg. 2010; 43:6-10.
Bhattacharya S. Burn epidemiology - an Indian perspective. Indian J Plast Surg. 2009;42:193-4.
Lee K, Joory K, Moiemen N. History of burns the past, present and the future. Burns Trauma 2014; 2:169-80.
Ansermino M, Hemseley C. Intensive care management and control of infection. BMJ. 2004; 329:220-3.
Mundhada SG, Waghmare PH, Rathod PG, Ingole KV. Bacterial and fungal profile of burn wound infections in tertiary care center. Indian J Burns. 2015;23:71-5.
Lunawat A, Sharma R, Kolla V, Patel S. Emerging resistance of higher antimicrobials and growing sensitivity of old antimicrobials against existing infections in burns. Int Surg J. 2015;2:385-91.
Chauhan JR, Khare S, Lal P, Kunhikatta V, Thunga G, Nair S, et al. An appraisal of antibiotic sensitivity pattern and drug utilization in burn patients. Indian J Burns. 2016;24:69-73.
Church D, Elsayed S, Reid O, Winston B, Lindsay R. Burn wound infections. Clin Microbiol Rev. 2006;19: 403-34.
Norbury W, Herndon D, Tanksley J, Jeschke M, Finnerty C. Infection in Burns. Surg Infect. 2016; 17:250-5.
Ramos G. Antibiotic prophylaxis in burn patients: a review of current trends and recommendations for treatment. J Infectiol. 2018;1:1-5.
Diederen B, Wardle C, Krijnen P, Tuinebreijer W, Breederveld R. Epidemiology of clinically relevant bacterial pathogens in a burn center in the Netherlands between 2005 and 2011. J Burn Care Res. 2015;36:446-53.
Vinitha CT, Tiwari P, Singh S, Rasania S, Khokkar A, Talwar R. Pattern and extent of hospital acquired wound infections in burns patients in a Delhi tertiary Care hospital. Indian J Prev Soc Med. 2011;42:79-81.
Banerjee B. Mahajan’s Methods in biostatistics for medical students and research workers. New Delhi: Jaypee Brothers; 2018:124-5.
Priyadarshini M, Kumar M, Sharma A K, Prashad A, Seema K. Bacteriological Profile and Antibiogram of Burn Wound Infections from Burn Patients at RIMS, Ranchi. Int J Med Res Prof. 2018; 4:203-6.
Jauhari S, Shalabh P, Goyal M, Prakash R, Juyal D. Bacteriological and Antimicrobial Sensitivity Profile of Burn Wound Infections in a Tertiary Care Hospital of Uttarakhand. Int J Curr Res. 2020;12:30-6.
Gupta M, Naik AK, Singh SK. Bacteriological profile and antimicrobial resistance patterns of burn wound infections in a tertiary care hospital. Heliyon. 2019;5; 1-4.
Erol S, Altoparlak U, Akcay MN, Celebi F, Parlak M. Changes of microbial flora and wound colonization in burned patients. Burns. 2004;30:357-61.
Bhatt P, Rathi K, Hazra S, Sharma A, Shete V. Prevalence of multidrug resistant pseudomonas aeruginosa infection in urn patients at a tertiary care center. Indian J Plast Surg. 2015;23:56-9.
De Macedo JL, Santos JB. Nosocomial infections in a Brazilian Burn Unit. Burns 2006;32:477-81.