Seroprevalence of antistreptolysin O antibodies in a tertiary health care centre in Haryana, India: a three year retrospective study


  • Aakanksha Sharma Department of Microbiology, PGIMS, Rohtak, Haryana
  • Shipra Agarwal Department of Microbiology, PGIMS, Rohtak, Haryana
  • Kiran Bala Department of Microbiology, PGIMS, Rohtak, Haryana
  • Uma Chaudhary Department of Microbiology, PGIMS, Rohtak, Haryana



Antistreptolyin O antibodies, Seroprevalence, ASO titer


Background: Presence of antistreptolysin O antibodies in a patient’s sera may be an isolated evidence of recent infection by group A or less commonly, group C or G Streptococcus, especially in patients suspected of having a non suppurative sequel to this infection.

Methods: A retrospective study was done on the sera samples received in the Department of Microbiology, PGIMS Rohtak, India for the detection of ASO, over a period of three years. The test was carried out by latex agglutination rapid test kit by Aspen.

Results: A total of 4632 samples were received in the laboratory during the study period. Of these, 1058 (22.8%) were found to be positive for the presence of ASO having titre of >200 IU/mL.

Conclusions: The prevalence of ASO was found to be highest in the age group 0-20. The presence of elevated streptococcal antibody titres in such a population reflects a high background prevalence of streptococcal infections. Thus, determination of ASO antibodies should be taken into consideration when evaluating the role of group A streptococcus in non-purulent complications of infections.


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How to Cite

Sharma, A., Agarwal, S., Bala, K., & Chaudhary, U. (2017). Seroprevalence of antistreptolysin O antibodies in a tertiary health care centre in Haryana, India: a three year retrospective study. International Journal of Research in Medical Sciences, 4(7), 2636–2638.



Original Research Articles