A clinico-epidemiological profile of Parkinson’s disease patients attending the tertiary care hospital of hilly state of North India: a hospital based cross-sectional study

Amethyst Bamon; Rajiv Raina; Sudhir Sharma; Nidhi Chauhan

doi:10.18203/2320-6012.ijrms20213088

Authors

Amethyst Bamon Department of Medicine, North Eastern Indira Gandhi Regional Institute of Health & Medical Sciences, Shillong, Meghalaya, India
Rajiv Raina Department of Medicine, IGMC, Shimla, Himachal Pradesh, India
Sudhir Sharma Department of Neurology, IGMC, Shimla, Himachal Pradesh, India
Nidhi Chauhan National Health Mission, Department of Health & Family Welfare, Himachal Pradesh, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20213088

Keywords:

Parkinson's disease, Hospital based study, Cross-sectional

Abstract

Background: Parkinson's disease (PD) is a neurodegenerative disorder, with male preponderance. It is associated with both motor and non-motor symptoms, which affect quality of life in elderly people. Due to paucity of studies on its epidemiology and prevalence, this disease needs assiduity and further exploration.

Methods: A hospital based cross-sectional study was conducted in the tertiary care hospital, among 45 patients diagnosed with PD.

Results: The mean age of the participants was 61.17±12.30 years, with male to female ratio was 2:1. The average age of onset of PD was 57.4±12.30 years. Tremor was the most common initial symptom (68.88%) followed by rigidity (20%) and bradykinesia. Most of the patients (86.66%) had progressive symptoms, and 69% had unilateral involvement of limbs.

Conclusions: The profile of patients with PD in Himachal Pradesh is similar to that from other populations in India and other developing countries. However, the dearth of studies and data pertaining to PD, invigorate the need to explore this neurodegenerative disorder to comprehend its clinic-epidemiological profile in our state.

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References

National Institute on Aging, 2017. Parkinson’s Disease. Available at: https://www.nia.nih.gov/health/parkinsons-disease. Accessed on 01 June 2021.

Radhakrishnan DM, Goyal V. Parkinson's disease: A review. Neurol India. 2018;66:26-35.

GBD 2016 Parkinson's Disease Collaborators. Global, regional, and national burden of Parkinson's disease, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2018;17(11):939-53.

Singhal B, Lalkaka J, Sankhla C. Epidemiology and treatment of Parkinson's disease in India. Parkinsonism Relat Disord. 2003;9(2):105-9.

Verma AK, Raj J, Sharma V, Singh TB, Srivastava S. Epidemiology and associated risk factors of Parkinson's disease among the North Indian population. Clinical Epidemiology and Global Health. 2017;5(1):8-13.

Femi OL, Ibrahim A, Aliyu S. Clinical profile of parkinsonian disorders in the tropics: Experience at Kano, northwestern Nigeria. J Neurosci Rural Pract. 2012;3(3):237-41.

Behari M, Srivastava AK, Das RR, Pandey RM. Risk factors of Parkinson's disease in Indian patients. J Neurol Sci. 2001;190(1-2):49-55.

Liu K, Gu Z, Dong L, Shen L, Sun Y, Zhang T, et al. Clinical profile of Parkinson's disease in the Gumei community of Minhang district, Shanghai. Clinics. 2014;69(7):457-63.

Lazarus JP, Vibha D, Handa KK, Singh S, Goyal V, Srivastava T, et al. A study of voice profiles and acoustic signs in patients with Parkinson's disease in North India. J Clin Neurosci. 2012;19(8):1125-9.

Tibar H, Bayad K, Bouhouche A, Haddou EH, Benomar A, Yahyaoui M, et al. Non-Motor Symptoms of Parkinson's Disease and Their Impact on Quality of Life in a Cohort of Moroccan Patients. Front Neurol. 2018;9:170.

Donald C, Winge K, Burn DJ. Lower urinary tract symptoms in Parkinson's disease: Prevalence, aetiology and management. Parkinsonism Relat Disord. 2017;35:8-16.