DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20213094

A randomized split mouth clinical trial of the application of the desensitizer agents for tooth sensitivity

K. Hanisha Reddy, Afroz Kalmee Syed, Dasarathi Alivelu, Haranath Danda, Ramya Alla

Abstract


Background: Dentin hypersensitivity (DH) affects 3%-75% of the people and is one of the morbid tooth conditions. Hence in the present study we aim to examine the clinical effectiveness of 3 different desensitizing agents in decreasing pain of DH in time of 1 month.

Methods: Fifty subjects with cervical DH in at least one tooth in any three of the 4 quadrants were selected. VAS was used to note the pain. Each quadrant in an individual was randomly assigned. Profluorid varnish, Admira protect, and PRG‑Barrier coat was used. VAS scores for the tactile and air stimuli were noted immediately after application, 1 week, and after 1 month. The data was analyzed keeping p<0.05 as significant.

Results: VAS significantly reduced for all three groups from the base line (p<0.001). Admira protect showed significant reduction of hypersensitivity scores at 1 month compared to other groups (p<0.001).

Conclusions: Admira protect was better at lowering the pain due to DH than PRG‑barrier coat and Profluorid varnish after 1 month of application.


Keywords


Random clinical trial, Desensitizing agents, Dental sensitivity

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References


Bissada NF. Symptomatology and clinical features of hypersensitive teeth. Arch Oral Biol. 1994;39(l):31S‑S.

Irwin CR, McCusker P. Prevalence of dentine hypersensitivity in a general dental population. J Ir Dent Assoc. 1997;43:7‑9.

Rees JS, Addy M. A cross‑sectional study of dentine hypersensitivity. J Clin Periodontol. 2002;29:997‑1003.

Chabanski MB, Gillam DG, Bulman JS, Newman HN. Clinical evaluation of cervical dentine sensitivity in a population of patients referred to a specialist periodontology department: A pilot study. J Oral Rehabil. 1997;24:666‑72.

Addy M, Dowell P. Dentine hypersensitivity – A review. Clinical and in vitro evaluation of treatment agents. J Clin Periodontol. 1983;10:351‑63.

Brannstrom M. The hydrodynamic theory of dentinal pain: Sensation in preparations, caries, and the dentinal crack syndrome. J Endod. 1986;12:453‑7.

Peacock JM, Orchardson R. Effects of potassium ions on action potential conduction in A‑ and C‑fibers of rat spinal nerves. J Dent Res. 1995;74:634‑41.

Markowitz K, Bilotto G, Kim S. Decreasing intra-dental nerve activity in the cat with potassium and divalent cations. Arch Oral Biol. 1991;36:1‑7.

Bekes K, John MT, Schaller HG, Hirsch C. Oral health‑related quality of life in patients seeking care for dentin hypersensitivity. J Oral Rehabil. 2009;36:45‑51.

Al‑Sabbagh M, Brown A, Thomas MV. In‑office treatment of dentinal hypersensitivity. Dent Clin North Am. 2009;53(7):47‑60.

Schuurs AH, Wesselink PR, Eijkman MA, Duivenvoorden HJ. Dentists’ views on cervical hypersensitivity and their knowledge of its treatment. Endod Dent Traumatol. 1995;11:240‑4.

Sheiham A, Maizels JE, Cushing AM. The concept of need in dental care. Int Dent J. 1982;32:265‑70.

Orchardson R, Gillam DG. Managing dentin hypersensitivity. J Am Dent Assoc. 2006;137:990‑8.

Kakaboura A, Rahiotis C, Thomaidis S, Doukoudakis S. Clinical effectiveness of two agents on the treatment of tooth cervical hypersensitivity. Am J Dent. 2005;18:291‑5.

Pamir T, Dalgar H, Onal B. Clinical evaluation of three desensitizing agents in relieving dentin hypersensitivity. Oper Dent. 2007;32:544‑8.

Pashley DH. Dentin permeability, dentin sensitivity, and treatment through tubule occlusion. J Endod. 1986;12:465‑74.

Gillam DG, Aris A, Bulman JS, Newman HN, Ley F. Dentine hypersensitivity in subjects recruited for clinical trials: Clinical evaluation, prevalence and intra‑oral distribution. J Oral Rehabil. 2002;29:226‑31.

Holland GR, Narhi MN, Addy M, Gangarosa L, Orchardson R. Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. J Clin Periodontol. 1997;24:808‑13.

Krauser JT. Hypersensitive teeth. Part II: Treatment. J Prosthet Dent. 1986;56:307‑11.

He S, Wang Y, Li X, Hu D. Effectiveness of laser therapy and topical desensitizing agents in treating dentine hypersensitivity: A systematic review. J Oral Rehabil. 2011;38:348‑58.

Porto IC, Andrade AK, Montes MA. Diagnosis and treatment of dentinal hypersensitivity. J Oral Sci. 2009;51:323‑32.

Malkoç MA, Sevimay M. Evaluation of mineral content of dentin treated with desensitizing agents and neodymium yttrium‑aluminium‑garnet (Nd: YAG) laser. Lasers Med Sci 2012;27:743‑8.

Pereira JC, Martineli AC, Tung MS. Replica of human dentin treated with different desensitizing agents: A methodological SEM study in vitro. Braz Dent J. 2002;13:75‑85.

Torres CR, Silva TM, Fonseca BM, Sales AL, Holleben P, Di Nicolo R et al. The effect of three desensitizing agents on dentin hypersensitivity: A randomized, split‑mouth clinical trial. Oper Dent. 2014;39:E186‑94.

Yu X, Liang B, Jin X, Fu B, Hannig M. Comparative in vivo study on the desensitizing efficacy of dentin desensitizers and one‑bottle self‑etching adhesives. Oper Dent. 2010;35:279‑86.

Samuel SR, Khatri SG, Acharya S, Patil ST. Evaluation of instant desensitization after a single topical application over 30 days: A randomized trial. Aust Dent J. 2015;60:336‑42.

Narongdej T, Sakoolnamarka R, Boonroung T. The effectiveness of a calcium sodium phosphosilicate desensitizer in reducing cervical dentin hypersensitivity: A pilot study. J Am Dent Assoc. 2010;141:995‑9.

Erdemir U, Yildiz E, Kilic I, Yucel T, Ozel S. The efficacy of three desensitizing agents used to treat dentin hypersensitivity. J Am Dent Assoc 2010;141:285‑96.