A randomized split mouth clinical trial of the application of the desensitizer agents for tooth sensitivity

K. Hanisha Reddy, Afroz Kalmee Syed, Dasarathi Alivelu, Haranath Danda, Ramya Alla


Background: Dentin hypersensitivity (DH) affects 3%-75% of the people and is one of the morbid tooth conditions. Hence in the present study we aim to examine the clinical effectiveness of 3 different desensitizing agents in decreasing pain of DH in time of 1 month.

Methods: Fifty subjects with cervical DH in at least one tooth in any three of the 4 quadrants were selected. VAS was used to note the pain. Each quadrant in an individual was randomly assigned. Profluorid varnish, Admira protect, and PRG‑Barrier coat was used. VAS scores for the tactile and air stimuli were noted immediately after application, 1 week, and after 1 month. The data was analyzed keeping p<0.05 as significant.

Results: VAS significantly reduced for all three groups from the base line (p<0.001). Admira protect showed significant reduction of hypersensitivity scores at 1 month compared to other groups (p<0.001).

Conclusions: Admira protect was better at lowering the pain due to DH than PRG‑barrier coat and Profluorid varnish after 1 month of application.


Random clinical trial, Desensitizing agents, Dental sensitivity

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