The acute effect of resistance exercise on serum growth hormone and blood glucose in healthy non-obese adolescent subject
DOI:
https://doi.org/10.18203/2320-6012.ijrms20212803Keywords:
Resistance training, Growth hormone, Glucose, Body mass indexAbstract
Background: The growth hormone (GH) response to resistance training is altered by many factors including sex steroid concentrations, fitness, intensity of exercise, age, gender, duration of exercise and glycemic state but the exact understanding of the interplay of different exercises to GH levels and its induced physiological adaptations is still obscure. This study aimed to see how resistance exercise affects GH levels and its correlation to plasma glucose levels in healthy non-obese adolescent subjects.
Methods: 48 healthy non-obese adolescent subjects, 24 males and 24 females were included in the study. High volume exercise training regimen was used which involved major muscle group of arms, legs and trunk. Pre and post exercise levels of serum GH and random blood sugar were estimated in male and female groups.
Results: The mean body mass index (BMI) of male and female groups was 23.22±3.12 kg/m2 and 20.40±4.49 kg/m2, respectively. The post-exercise serum GH levels in male and females increased significantly by 0.54±1.041 ng/ml (p<0.05) and 0.85±1.023 ng/ml (p<0.001) respectively. The random blood sugar levels in males after exercise significantly increased (p<0.05) by 7.16±12.61 mg/dl and in females by 6.20±12.09 mg/dl (p<0.05). There was significant correlation (p<0.05) between increase in serum GH levels and increase in random blood sugar levels in both male and female group.
Conclusions: Exercise induced increase in GH and its interplay with serum glucose can be better gained access into via metanalytical/elaborate studies of the major hormones and fuels involved.
Metrics
References
Kraemer, William &Vingren, Jakob & Hatfield, Disa & Spiering, B.A. & Fragala, M.S. (2007). Resistance training program. ACSM's resources for the personal trainer. 372-403.
Izquierdo M, Ibañez J, Calbet JAL, Navarro-Amezqueta I, González-Izal M, Idoate F, et al. Cytokine and hormone responses to resistance training. Eur J Appl Physiol. 2009;107(4):397-409.
Rønnestad BR, Nygaard H, Raastad T. Physiological elevation of endogenous hormones results in superior strength training adaptation. Eur J Appl Physiol. 2011;111(9):2249-59.
McCall GE, Byrnes WC, Fleck SJ, Dickinson A, Kraemer WJ. Acute and chronic hormonal responses to resistance training designed to promote muscle hypertrophy. Can J Appl Physiol. 1999;24(1):96-107.
Schoenfeld BJ. The mechanisms of muscle hypertrophy and their application to resistance training. J Strength Cond Res. 2010;24(10):2857-72.
WHO. Obesity and overweight Fact sheet N°311 September 2006.
"Immunoassays site.iugaza.edu.ps." Available at: http://site.iugaza.edu.ps/hesawwaf/files/2016/02/Immunoassays-ELISA-part-two-growth-hormon.pptx. Accessed on 3 March 2021.
Bio Vision. Fact sheet: Human Growth Hormone ELISA Kit. Available at: https://www.biovision. com/documentation/datasheets/K7412.pdf. Accessed on 30 May 2021.
Manini TM, Yarrow JF, Buford TW, Clark BC, Conover CF, Borst SE. Growth hormone responses to acute resistance exercise with vascular restriction in young and old men. Growth Horm IGF Res. 2012;22(5):167-72.
Cook DM. Growth hormone and estrogen: a clinician's approach. J Pediatr Endocrinol Metab. 2004;17(4):1273-6.
Kreitschmann-Andermahr I, Suarez P, Jennings R, Evers N, Brabant G. GH/IGF-I regulation in obesity-mechanisms and practical consequences in children and adults. Horm Res Paediatr. 2010;73(3):153-60.
Green LE, Dinh TA, Smith RA. An estrogen model: the relationship between body mass index, menopausal status, estrogen replacement therapy, and breast cancer risk. Comput Math Methods Med. 2012;2012:792375.
Mulligan S, Fleck S, Gordon S, Koziris L, Triplett-McBride N, Kraemer W. Influence of resistance exercise volume on serum growth hormone and cortisol concentrations in women. J Streng Condition Res. 1996;10(4):256-62.
Centers for Disease Control and Prevention. Fact sheet: About Child and Teen BMI, 2018. Available at: www.cdc.gov/healthyweight/assessing/ bmi/childrens_BMI/about_childrens_BMI.html. Accessed on 30 May 2021.
Awadh FA, ALRamadhan F, =Baaleis M, Alhanwah B. Correlation between body mass index and blood glucose levels among female students of King Faisal university. Int J Sci Eng Res. 2018;9(1):998-1003.
ISSUU. Fact sheet: Mechanisms of muscle hypertrophy by Guan, 1966. Available at: https://issuu.com/guan1966/docs/mechanisms_of_muscle_hypertrophy. Accessed on 30 May 2021.
Ahtiainen JP, Pakarinen A, Alen M, Kraemer WJ, Häkkinen K. Muscle hypertrophy, hormonal adaptations and strength development during strength training in strength-trained and untrained men. Eur J Appl Physiol. 2003;89(6):555-3.