Cyto-histological correlation of salivary gland lesions- a prospective study in a tertiary care institute

Authors

  • Soma Negi Department of Pathology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
  • Kavita Mardi Department of Pathology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
  • Shivani Sood Department of Immuno Haematology and Blood Transfusion, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
  • Neelam Gupta Department of Pathology, Maharishi Markande University, Solan, Himachal Pradesh, India
  • N. K. Mohindroo Department of Oto-rhino-laryngology, Principal, Y. S. Parmar Medical College, Nahan, Himachal Pradesh, India
  • Muninder Kumar Department of Radiotherapy, Dr. Rajendra Prasad Government Medical College, Tanda, Himachal Pradesh, India
  • Ramesh Azad Department of Oto-rhino-Laryngology Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
  • Ashish Chaudhary Department of Pathology, Pt. Jawahar Lal Nehru Government Medical College and Hospital, Chamba, Himachal Pradesh, India
  • Gunjita Negi Third year MBBS, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20220286

Keywords:

Cyto-histological correlation, FNAC, Salivary glands

Abstract

Background: Fine needle aspiration cytology (FNAC) has an essential proven role in diagnosing most of the common and benign salivary gland lesions. However, limited cellularity and morphological heterogeneity of the lesion can pose diagnostic challenges. The present study was conducted in a tertiary care centre over a period of one year with an objective to study the cyto-morphological features of salivary gland lesions and correlate cytological findings with histopathology.

Methods: The study was carried out over a period of one year from January 2014 to December 2014. FNA specimens obtained from 78 patients were analyzed. Of these, only 51 patients underwent biopsy or surgery and their specimens were subjected to histopathological examination. Validation of cytological diagnosis was done on the basis of histopathological diagnosis.

Results: A total 78 patients with salivary gland lesions were subjected to FNAC. Non neoplastic lesions constituted 19 cases (25%) and benign lesions constituted 46 cases (80.70%).  Malignant lesions constituted 11 cases (19.30%). Two cases were inconclusive due to inadequate aspirated material. Overall sensitivity, specificity and diagnostic accuracy were 95.98%, 99.20% and 98.09% respectively.

Conclusions: FNAC continues to be an accurate diagnostic technique in the hands of an experienced cytopathologist. It is a highly sensitive and specific technique for rapid diagnosis of most of the salivary gland swellings.

Author Biographies

Soma Negi, Department of Pathology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India

Assistant Professor, Deptt. Of Pathology, Dr. Rajender Prasad Government Medical College, Tanda

Kavita Mardi, Department of Pathology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India

Professor, Deptt. of Pathology, Indira Gandhi Medical College, Shimla

Shivani Sood, Department of Immuno Haematology and Blood Transfusion, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India

Assistant Professor, Deptt. of Immunohematologfy and BloodTransfusion, Indira Gandhi Medical College, Shimla

Neelam Gupta, Department of Pathology, Maharishi Markande University, Solan, Himachal Pradesh, India

Professor, Deptt. Of Pathology, Maharishi Markande University, Solan

N. K. Mohindroo, Department of Oto-rhino-laryngology, Principal, Y. S. Parmar Medical College, Nahan, Himachal Pradesh, India

Principal, Y S Parmar Medical College, Nahan

Muninder Kumar, Department of Radiotherapy, Dr. Rajendra Prasad Government Medical College, Tanda, Himachal Pradesh, India

Professor, Deptt. Of Radiotherapy, Dr. Rajender Prasad Government Medical College, Tanda

Ramesh Azad, Department of Oto-rhino-Laryngology Indira Gandhi Medical College, Shimla, Himachal Pradesh, India

Professor, Deptt. of Oto-rhino-laryngology, Indira Gandhi Medical College, Shimla

Ashish Chaudhary, Department of Pathology, Pt. Jawahar Lal Nehru Government Medical College and Hospital, Chamba, Himachal Pradesh, India

Assistant Professor, Pt. Jawahar Lal Nehru Government Medical College And Hospital, Chamba

Gunjita Negi, Third year MBBS, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India

All India Institute Of Medical Sciences, Rishikesh

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Published

2022-01-29

How to Cite

Negi, S., Mardi, K., Sood, S., Gupta, N., Mohindroo, N. K., Kumar, M., Azad, R., Chaudhary, A., & Negi, G. (2022). Cyto-histological correlation of salivary gland lesions- a prospective study in a tertiary care institute. International Journal of Research in Medical Sciences, 10(2), 425–430. https://doi.org/10.18203/2320-6012.ijrms20220286

Issue

Vol. 10 No. 2 (2022): February 2022

Section

Original Research Articles