@article{Debnath_Savaliya_Patel_Patel_2020, title={EDTA contamination: a preanalytical cause for interference in iron and unsaturated iron binding capacity assay}, volume={8}, url={https://www.msjonline.org/index.php/ijrms/article/view/8054}, DOI={10.18203/2320-6012.ijrms20202253}, abstractNote={<p class="abstract"><strong>Background:</strong> The aim of the study is focussed very keenly at performing RCA (root cause analysis) of those particular sample containing the absurd results of the Serum UIBC (Unsaturated Iron Binding Capacity), which was also tallied vigilantly side by side with Serum Iron observed at Clinical Biochemistry laboratory of The New Civil Hospital Surat, Gujarat.</p><p class="abstract"><strong>Methods:</strong> The Absurd value from the samples requested for Serum Iiron and Serum Serum UIBC (Unsaturated Iron Binding Capacity) from month of August 2018 till the month of August 2019 were taken in to account for analysis. RCA (root cause analysis) of absurd value for Serum Iron and Serum UIBC (Unsaturated Iron Binding Capacity) which were prepared was mainly focused on tallying with Serum Calcium and Serum Potassium result.</p><p class="abstract"><strong>Results:</strong> With the continious and strenous monitoring from the side of the researchers, the researchers had throughly analysed and found that in almost all of those analysed test containing absurd results of Serum Iron and Serum UIBC(Unsaturated Iron Binding Capacity) which were some way or the other, associated with absurd results of Serum Calcium along with absurd result of Serum Potassium too from the same samples.</p><p class="abstract"><strong>Conclusions:</strong> The Absurd results of Serum Calcium and Serum Potassium are caused mainly due to pre-analytical errors more likely due to the sample contamination with EDTA (ethylene diamine tetra acetic acid). The contaminated EDTA (ethylene diamine tetra acetic acid) sample cause interference in Serum Iron measurement by producing turbidity in sample and in Serum UIBC (Unsaturated Iron Binding Capacity) by chelating Iron.</p>}, number={6}, journal={International Journal of Research in Medical Sciences}, author={Debnath, Chapal and Savaliya, Niral G. and Patel, Nikunj R. and Patel, Chinka}, year={2020}, month={May}, pages={2117–2122} }