@article{Parashar_Singh_Sharma_Raval_2021, title={Comparison between isobaric levobupivacaine 0.5% and hyperbaric bupivacaine 0.5% in spinal anesthesia in lower limb surgeries and lower abdominal surgeries in adult patients}, volume={9}, url={https://www.msjonline.org/index.php/ijrms/article/view/8848}, DOI={10.18203/2320-6012.ijrms20210417}, abstractNote={<p><strong> </strong></p><p class="abstract"><strong>Background:</strong> The aim of our study was to compare sensory and motor block characteristics and hemodynamic changes following intrathecal hyperbaric bupivacaine (0.5%) and isobaric levobupivacaine (0.5%) in elective lower limb and lower abdominal surgeries.</p><p class="abstract"><strong>Methods:</strong> 60 patients of either sex, aged 18-60 years, ASA grade I or II scheduled for elective lower abdominal and lower limb surgeries were randomized into two groups, group B (n=30) and group L (n=30) and received either 3 ml of intrathecal hyperbaric bupivacaine or isobaric levobupivacaine intrathecally.</p><p class="abstract"><strong>Results:</strong> The mean time of onset of sensory block at shin of tibia in both the groups was comparable i.e. levobupivacaine (1.19±0.2 minutes) and bupivacaine (1.1+0.2 minutes). The mean time for total duration of sensory block was 211.1±8.2 minutes in group L, while 193.13±13.7 minutes in group B. Time for total duration of motor block in group L was 198.76±8.428 minutes and in group B was 182.6±13.989 minutes. Statistically significant difference was observed in total duration of sensory and motor block in both levobupivaciane and bupivacaine group (p<0.0001). Patients in group L were hemodynamically more stable with significantly less decrease in pulse rate, systolic blood pressure and diastolic blood pressure as compared to group B.</p><p class="abstract"><strong>Conclusions:</strong> We observed that 0.5% isobaric levobupivacaine provided better hemodynamic stability, longer duration of sensory and motor block as compared to bupivacaine.</p><p class="abstract"> </p>}, number={2}, journal={International Journal of Research in Medical Sciences}, author={Parashar, Preeti and Singh, Anisha and Sharma, Manoj Kumar and Raval, Dipak L.}, year={2021}, month={Jan.}, pages={418–422} }