TY - JOUR AU - Haridas, Abhilash AU - Mukker, Payal AU - Pandey, Sanjay AU - Parashar, Manoj Kumar AU - Mehta, Virender Kumar PY - 2016/12/18 Y2 - 2024/03/29 TI - Assessment of endothelial dysfunction in diabetes mellitus in Indian population by color Doppler JF - International Journal of Research in Medical Sciences JA - Int J Res Med Sci VL - 4 IS - 9 SE - Original Research Articles DO - 10.18203/2320-6012.ijrms20162915 UR - https://www.msjonline.org/index.php/ijrms/article/view/159 SP - 3956-3962 AB - <p><strong>Background:</strong> Endothelial dysfunction is regarded as a systemic marker of cardiovascular disease. Brachial artery flow-mediated dilation (FMD) is a mode of evaluating endothelial function and for early diagnosis of atherosclerotic diseases. We studied whether there is a difference in vascular endothelial function between type 1 and 2 diabetes mellitus and normal population.</p><p class="abstract"><strong>Methods:</strong> We assessed %FMD of 50 patients with diabetes mellitus and 50 control populations without diabetes mellitus or other risk factors. SPSSS version 13 was used for statistical analysis. Students T test was used for comparison of means of the two groups.</p><p class="abstract"><strong>Results:</strong> The %FMD was significantly lower in patients with type1 and 2 diabetes mellitus compared to normal population.</p><p class="abstract"><strong>Conclusions:</strong> Diabetes mellitus is associated with endothelial dysfunction irrespective of Type 1 or Type 2 diabetes mellitus, as suggested by impairment in vascular reactivity to hyperemia in both. Monitoring FMD may help in assessment of progression of atherosclerosis.</p> ER -