TY - JOUR AU - Kriplani, Dipsha AU - Kriplani, Akshay AU - Gupta, Vivek AU - Samal, N. AU - Bhake, Arvind AU - Mahajan, Satish PY - 2017/01/10 Y2 - 2024/03/28 TI - Correlation of glycosylated hemoglobin with microalbuminuria to predict renal damage in diabetic patients JF - International Journal of Research in Medical Sciences JA - Int J Res Med Sci VL - 3 IS - 8 SE - Original Research Articles DO - 10.18203/2320-6012.ijrms20150318 UR - https://www.msjonline.org/index.php/ijrms/article/view/1647 SP - 2014-2019 AB - <p class="abstract"><strong><span lang="EN-US">Background:</span></strong><span lang="EN-US"> Regular screening of levels of glycosylated hemoglobin and microalbuminuria, diabetic nephropathy can be prevented. The aim was to </span><span lang="EN-US">assess and compare the levels of glycosylated hemoglobin, microalbuminuria and serum creatinine in type 2 diabetic patients divided in groups of those on default antidiabetic treatment compared with those on regular antidiabetic treatment and to assess its correlation in type 2 of diabetic nephropathy. </span></p><p class="abstract"><strong><span lang="EN-US">Methods:</span></strong><span lang="EN-US">Two hundred diabetic patients above 40 years of age</span><span lang="EN-US"> and 200 age matched control subjects with levels of glycosylated hemoglobin &lt; 6.5% and on regular antiglycemic therapy were selected. </span><span lang="EN-US">Fasting plasma sugar was estimated by the glucose oxidase (GOD) - glucose peroxidase (POD). <span>Glycosylated hemoglobin and </span>microalbuminuria<span> level was measured by the immunoturbidimetric method and </span>serum creatinine estimation was done by the Jaffe’s kinetic method. <em>p</em> value was drawn using the student’s paired t-test. </span></p><p class="abstract"><strong><span lang="EN-US">Results:</span></strong><span lang="EN-US"> There is a strong correlation between the increase in the levels of glycosylated hemoglobin with the corresponding rise in the levels of microalbuminuria and serum creatinine. </span></p><p class="abstract"><strong><span lang="EN-US">Conclusion:</span></strong><span lang="EN-US"> Periodic surveillance of the levels of microalbuminuria should be carried out in the type 2 diabetic patients to prevent further damage by early detection of diabetic nephropathy.</span></p><p class="abstract"> </p> ER -