Therapeutic applications of stem cells from human exfoliated deciduous teeth: a review

Authors

  • Mani Baweja Consultant Dentist at Clove Dental, New Delhi, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20203705

Keywords:

Human deciduous teeth dental pulp cell, Human exfoliated deciduous teeth, Stem cell

Abstract

Dental stem cells have been found to have the ability to differentiate into nerve cells, adipose cells, chondrocytes, osteoblasts, myocytes, hepatocytes, and odontoblasts. They can be derived from permanent teeth or deciduous teeth. Stem cells from human exfoliated deciduous teeth (SHED) have a higher proliferation rate and higher osteogenic and neurogenic potential than dental pulp stem cells (DPSC). Therefore, SHEDs are an attractive cell source for tissue regeneration. A large plethora of in vitro and animal studies have been conducted in the last few decades that has demonstrated the potential uses of these cells for the treatment of oral and non-oral diseases. The aim of this article was to review the potential therapeutic applications of stem cells derived from human exfoliated deciduous teeth. A Medline search was done, including international literature, published in English between 2003 and 2020. In this area, further research is needed to ensure the applicability of SHED in the treatment of diseases in humans.

Author Biography

Mani Baweja, Consultant Dentist at Clove Dental, New Delhi, India

BDS- Maulana Azad Institute of Dental Sciences, Delhi

MDS- University College of Medical Sciences, Delhi

Senior Resident- Sanjay Gandhi Memorial Hospital, Delhi

Visiting Consultant in Delhi

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Published

2020-08-26

How to Cite

Baweja, M. (2020). Therapeutic applications of stem cells from human exfoliated deciduous teeth: a review. International Journal of Research in Medical Sciences, 8(9), 3413–3417. https://doi.org/10.18203/2320-6012.ijrms20203705

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Section

Review Articles