Acute onset monoparesis in newly diagnosed patients with type 2 diabetes mellitus with poor glycemia

Rohit Raina, Mukaresh Fatima, Areca Wangnoo


In newly diagnosed patients with diabetes with poor glycemia, presentation is sometimes acute onset monoparesis, which eventually improved with good glycemic control. To report an unusual patient with newly diagnosed diabetes whose initial manifestation was acute onset monoparesis. A 58-year old female patient with new onset type 2 diabetes mellitus with diabetic ketoacidosis (DKA) who presented to us with acute onset monoparesis (right lower limb) lower motor neuron (LMN) type without bladder involvement, secondary to poor glycemia which eventually resolved with good glycemic control.


Diabetes, Monoparesis, Poor glycemia

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Raff MC, Sangalang V, Asbury AK. Ischemic Mononeuropathy associated with diabetes mellitus. Arch Neurol. 1968;18(5):487-9.

Kelkar P, Parry GJ. Mononeuritis multiplex in diabetes: evidence for underlying immune pathogenesis. J Clin Neuromusc Dis. 2000;2:116-8.

Popovic R, Obradovic D, Martic V, Raicevic R, et al. Painful monoparesis of the arm caused by plexopathy in unrecognized diabetes mellitus. Clin Neurophysiol. 2015;126(9):e183-e4.

Pica EC, Verma KK. Bilateral brachial plexopathy as an initial presentation in a newly diagnosed, uncontrolled case of diabetes mellitus. Singapore Med J. 2008;49(2):e29-32.

Santillan CE, Katirji B. Brachial Plexopathy in Diabetes Ketoacidosis. Muscle Nerve. 2000;23(2):271-3.

Massie R, Mauermann ML, Staff NP, Amrami KK, Mandrekar JN, Dyck PJ, et al. Diabetic cervical radiculoplexus neuropathy: a distinct syndrome expanding the spectrum of diabetic radiculoplexus neuropathies. Brain. 2012;135(10):3074-88.

Sander HW, Chokroverty S. Diabetic Amyotrophy: current concepts. Semin Neurol. 1996;16(2):173-8.

Rydberg M, Zimmerman M, Gottsater A, Nilsson PM, Melander O, Dahlin LB. Diabetes mellitus as risk factor for compression neuropathy: a longitudinal cohort study from southern Sweden. BMJ Open Diabetes Res Care. 2020;8(1):1298.

Kocer A, Domac FM, Boylu F, Us O,Tanrida─č T. A comparison of sural nerve conduction in patients with impaired oral glucose tolerance test. Acta Neurol Scand. 2007;116(6):399-405.

Ogawa K, Sasaki H, Kishi Y, Yamasaki H, Okamoto K, Yamamoto N, et al. A suspected case of proximal diabetic neuropathy predominantly presenting with scapulohumeral muscle weakness and deep aching pain. Diabetes Res Clin Pract. 2001;54(1):57-64.